CLAIRITY Particle Image Analytics Software Suite

PRECISE: Utilizing advanced image analytics, CLAIRITY™ delivers precise particle sizing, distribution and morphological analysis.
COMPATIBLE: From powders and liquids to suspensions, granulations, creams, or ointments, CLAIRITY™ can observe particle and globule size in almost any matrix.
ADAPTABLE: With a high-resolution camera CLAIRITY™ makes traditional particle size analysis more accessible to every lab, every day, processing images from virtually any source.
ACCESSIBLE: CLAIRITY™ boasts an intuitive and user-friendly interface that can be installed as stand-alone, LIMS integrated, or cloud-based.
OPTIMIZED: Designed with users in mind, CLAIRITY™ provides the needed functionalities without the complexities.
COMPLIANT: With 21 CFR Part 11 built-in; CLAIRITY™ meets the rigorous requirements of data compliance for regulated markets
FUNCTIONAL: CLAIRITY™ enables predictive modelling, anomaly detection, and comprehensive data interpretation, expediting decision-making and establishing functional relationships between material attributes and product quality.

CLAIRITY™ can…

USP COMPLIANCE
Assist in meeting standards for particulate analysis according to USPs <787>, <788>, <790> for sterile product formulations on solid filter paper substrates.

CONTENT AND BLEND UNIFORMITY
Utilize pattern recognition algorithm to correctly speciate and differentiate a 4-component blend and perform blend uniformity analysis to validate manufacturing process.

BIOEQUIVALANCE
Identify a product bioequivalence failure traditional methods couldn’t find, and assist in root cause analysis, correctly identifying the failed batches, and a milling/crystallization problem.

FORMULATION - QUALITY ASSURANCE
Assist in the final lot release of a two API component ointment, accurately identifying each component in the ointment according to size and morphological properties.

VISUAL INSPECTION - GLASS DELAMINATION
Visually detect, identify, and quantify glass shards delaminated from the surface of an intact glass vail, in conjunction with a stereo-microscope.

REANALYZE DATASETS
Datasets obtained from flow imaging techniques and other sources are data-rich. CLAIRITY™ can be used to reanalyze these data sets ease and simplify data interpretation and intercomparability.

IN-PROCESS CRYSTALLIZATION
CLAIRITY™ can process images from a variety of sources to assess particle size, in this example an in-situ process monitoring camera was used to capture and monitor crystal growth rate and shape.

CFU COUNTING
The CLAIRITY™ MICROBE module is specifically designed for cell and microbial colony counting, providing data-rich information including color, shape and more for each colony found.

ACCEPTANCE TESTING
Training CLAIRITY™ with historical data or samples for incoming material acceptance testing allows it to be trained to take over the process, potentially avoiding time consuming revalidation.

THE FINAL INTERCOMPARABILITY REFEREE
With over 25 reported parameters, CLAIRITY™ reports every instrument manufacturers measurement of size, providing system comparability, that is system and manufacturer agnostic.

But which size...?

When it comes to the measurement of particle size, there is no single answer to the conundrum of which size metrics to report. Techniques like Laser Diffraction report volumetric distributions, while image analysis techniques report number distributions. Even different manufacturers report different size and shape parameters for identical particles, resulting in incomparable data sets. CLAIRITY™™ is the common voice in the world of particle analysis, as it is designed to analyze particles and report results from multiple sources or instruments in a common format defined by the acquisition method itself.

CLAIRITY™ Suite of Particle Visualization and Characterization Tools